Christof Regl's and Therese Wohlschlager's study into the performance characteristics of HPLC-MS for analyzing multiple attributes of therapeutic antibodies at the intact protein level was accepted for publication in mAbs. The study was initiated by Johann Holzmann and first experiments were performed quite some time ago by Iris Wagner and Martin Samonig.
For the 14th time, researchers and stakeholders of the Christian Doppler Laboratory met to exchange progress made and discuss new ideas. Thanks to Rowan Moore and Frank Steiner for hosting this meeting at the Thermo Fisher Scientific site in Germering!
Sabrina Wildner's and Gabirele Gadermaier's study into aptamer selection of interaction with therapeutic proteins entitled Aptamers as quality control tool for production, storage and biosimilarity of the anti-CD20 biopharmaceutical rituximab has been accepted by Scientific Reports. Preprint will follow soon. Very pleasing!
Another opportunity to tell the story of antibody characterization by HPLC-MS methods. Remarkably, the organizer of the conference, Frantisek Foret, was honored with the Csaba Horváth Memorial Lectureship Award presented by the American Chemical Society (on the picture together with Andras Guttmann and Ference Darvas, President of the Awards Committee American Chemical Society Hungary Chapter). Congratulations!
The group picture (lower right) shows Csaba Horváth's group from 1996 in New Haven, when Frantisek was still associated with the Barnett Institute of Northeastern University in Boston, only 150 miles away from Csaba's labs at Yale University.
Luigi Grassi's, Christof Regl's and Mario Schubert's paper on the assignment of succinimide chemical shifts in peptides and proteins got accepted in Analytical Chemistry ( DOI: 10.1021/acs.analchem.7b01645).