Symposium of the doctoral college Immunity in Cancer and Allergy and the Doctoral School PLUS Biomolecules at the University of Salzburg. Christian Doppler Lab members Michael Kohlberger and Arthur Hinterholzer publicly presented their dissertation projects during the symposium: Identification of Aptamers for Host Cell Protein Detection (supervision: Fatima Ferreira-Briza und Gabriele Gadermaier) and Detection and quantification of post-translational modifications in biopharmaceuticals with NMR-Spectroscopy (supervision: Chiara Cabrele und Mario Schubert). Well done!

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Christof Regl's and Therese Wohlschlager's insights into the characterization of methionine oxidation in Rituximab by HPLC-MS have been collected in a Case Study entitled A Platform Method for Oxidation Monitoringin Monoclonal Antibodies and Fc-FusionProteins — A Biopharmaceutical Method Development Case Study, available from the Thermo Fisher Scientific website. Thanks Rowan Moore and Stacy Tremintin for the collaboration!

Therese Wohlschlager's publication Native mass spectrometry combined with enzymatic dissection unravels glycoform heterogeneity of biopharmaceuticals in Nature Communications has been recognized with the Publication of the Month Award of the Department of Biosciences. Open access article can be found here.

Again, pharma/biopharma was a hot topic at the 42nd ISCC in Riva del Garda. Using data elaborated by Christof Regl and Therese Wohlschlager, Christian Doppler Laboratory Head Christian Huber presented a critical check on the capabilities of chromatography and mass spectrometry with respect to revealing oxidation in biopharmaceuticals. Details will follow soon in a short article to be published in the LCGC Biopharmacuetical Perspectives Column.

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After a number of struggles, Therese Wohlschlager's work on deciphering highly complex glycosylation in a therapeutic fusion protein using enzymatic tools and native mass spectrometry finally got published in Nature Communications. Full text is available here.