Last week, CD Lab scientists attended the ANAKON conference in Münster/Germany. Highlights, among a number of highly interesting presentations dealing with analytical sciences were:

  1. The chairman of the conference, Prof. Uwe Karst, receiving the Hans-Malissa-Sen.-Lecture Award of the Austrian Society of Analytical Chemistry.
  2. Dr. Stefan Lamotte, BASF, receiving the Gerhard Hesse Award of the German Chemical Society/Working Group Separation Science.
  3. Constantin Blöchl presenting his work in a lecture entitled Middle-Up Analysis of Murine IgG Reveals Changes in N-Glycosylation upon Antigen Vaccination. This lecture has been recognized with the Agnes and Isván Halász Young Scientist Award. Congratulations Constantin!
  4. Christof Regl presenting his work Dilute-and-Shoot Analysis of Therapeutic Monoclonal Antibody Variants in Fermentation Broth: A Method Capability Study.
  5. Christian Huber talking about The Search for Impurities in Low- and High-Molecular Pharmaceuticals: Two Different Worlds.

20190401 anakon

The symposium Celebration of Native Mass Spectrometry was held in Oxford, 24-26th March 2019, with 160 participants. Prof. Carol Robinson opened the conference with a plenary lecture entitled Native MS – Past, Present, Future. The symposium covered the application of native MS in structural biology, biopharma characterization and membrane protein analysis, as well as theoretical considerations on proteins in the gas phase. The last session provided an outlook on the future of structural MS, native top-down and new methods & workflows. Remain Creative with Native was the motto of the closing plenary lecture given by Prof. Albert Heck. Other talks: Ken Cook on chromatographic separation coupled to native mass spectrometry; Therese Wohlschlager on native MS unravelling highly complex glycosylation patterns in therapeutic proteins.

Mario Schubert's and colleagues' study into protein gluconoylation by denaturing NMR has been published in the Journal of Biomolecular NMR. Another convincing example of our multidisciplinary approach to protein biochemistry involving NMR spectroscopy, mass spectrometry, structural biology, and bioorganic chemistry. Full article is available here.

In front of a demanding jury headed by the vice president of the Christian Doppler Society, the researchers presented the scientific progress in the Christian Doppler Laboratory. Students and postdocs were very well prepared, presented excellent talks, and gave a very positive impression to the evaluaters (see picture of Christof Regl "dancing" the structure of a monclonal antibody). Also our industry partners (Urs Lohrig from Novartis, Rowan Moore from Thermo Fisher Scientific) were communicating a very appreciative view of the collaboration. Feedback of the evaluators was positive, so we have hope for a continuation of the project for another two years.

180725 evaluation