Host cell protein detection in the focus: experimental and computational wordflows

22 July 2020

Host cell protein detection in the focus: experimental and computational wordflows

A comprehensive investigation of experimental and computational workflows for host cell protein detection in biopharmaceuticals performed by Wolfgang Esser-Skala, Marius Segl and Therese Wohlschlager has been published recently in Analytical and Bioanalytical Chemistry.

08 June 2020

Experimental and computational workflow to correct for hexosylation in the determination of glycan profiles has been published in Angewandte Chemie

Wolfgang Skala's, Therese Wohlschlagers's, and Christof Regl's workflow to correct for hexosylation bias in intact-protein glycan profiles was published in Angewandte Chemie. The reviewers rated the work as among the 10% most important manuscripts reviewed for Angewandte Chemie. Excellent achievment!

07 May 2020

Study on mAB fermentation in collaboration with CD Lab at TU Vienna accepted for publication

The mechanistic study performed by Katharina Böttinger in collaboration with the Christian Doppler Laboratory of Mechanistic and Physiological Methods for Improved Bioprocesses headed by Prof. Christoph Herwig entitled Development, characterization and application of a 2-Compartment System to investigate the impact of pH inhomogeneities in large-scale CHO based processes was accepted for publication in Engineering in Life Sciences. Well done!

24 January 2020

Merck-Award for PhD Theses in Sciences 2019 presented to Christof Regl

Christof Regl's PhD Thesis entitled Quantification and Site Specific Assignment of Post-translational Modifications in Monoclonal Antibodies was recognized with the Merck-Award for PhD Theses in Sciences 2019. Prof. Jörg von Hagen of Merck GmbH, Darmstadt, emphasized the tremendous importance of in-depth protein characterization in the pharmaceutical industry in order to guarantee the safety and quality of protein-based pharmaceuticals.

Congratulations!

24 January 2020

Therese Wohlschlager considered a "Rising Star of Separation Science"

In a recent LC-GC Europe supplement, winners of poster awards at ICS 2018 in Cannes-Mandelieu/France and HPLC 2019 in Milan/Italy have been interviewed about their research and scientific perspectives Therese Wohlschlager recalls her poster presented in Cannes entitled Dilute-and-Shoot Analysis of Therapeutic Monoclonal Antibody Glycosylation from Fermentation Broth: A Method Capability Study. Congratulations!

13 January 2020

30th Jubilee Meeting of PhD Students in the Field of Separation Science

Katharina Böttinger and Christian Huber attended the 30th Jubilee Meeting of PhD Students in the Field of Separation Science organized by the Working Group Separation Science of the German Chemical Society. The program featured a number of high-class presentations focusing on all aspects of modern spearation techniques, including a presentation entitled Glycosylation Profiling of Intact Monoclonal Antibodies by IP-RP HPLC-MS given by Katharina (full program here). Highlight of the anniversary party was music presented by the group Chemists after Dark featuring Saarbrücken Alumni Frank Steiner, Jochen Saar, and Stephan Lamotte, as well as Salzburg Alumnus Volker Neu: excellent performance and lots of fun!