Paper Publications

Peer-reviewed

Dall E., Fegg J. C., Briza P., Brandstetter H.
Structure and mechanism of an aspartimide-dependent peptide ligase in human legumain
Angew. Chem. Int. Ed. Engl. 54(10), 2917–2921 (2015)

Huber C. G.
Higher order mass spectrometry techniques applied to biopharmaceuticals
"Advances in Biopharmaceutical Analysis" supplement to LCGC Europe 28(s10) 31–36 (2015)

Forstenlehner I., Holzmann J., Toll H., Huber C. G.
Site-specific characterization and absolute quantification of pegfilgrastim oxidation by top-down high-performance liquid chromatography-mass spectrometry
Anal. Chem. 87(18), 9336–9343 (2015)

without peer review

Huber C. G., Wohlschlager T., Tevini J., Steiner F.
Piecing Together Protein Analysis
The Medicine Maker, Issue 11/2015

Monography

Gadermaier G., Stemeseder T., Hemmer W., Hawranek T.
Markerallergene von Kräuterpollen: diagnostischer Nutzen im klinischen Alltag
in: Kleine-Tebbe J., Jakob T. (eds.): Molekulare Allergiediagnostik, Springer, Berlin/Heidelberg, 193–204 (2015)

Participation in Conferences

Invited Talks

Wohlschlager T.
Characterization and quantification of pegfilgrastim oxidation variants by top-down HPLC-MS
Practical seminar in biotherapeutic protein characterization, Vienna (Austria), 20.–22.04.2015

Stutz H.
Application of capillary electrophoresis in the characterization of recombinant proteins and biopharmaceuticals
University of Pavia, Department of Drug Sciences, Pavia (Italy), 21.05.2015

Gadermaier G.
English plantain pollen allergy – resolving the miracle using Pla l 1 for structural and immunological analysis
Pirquet Club AKH Wien, Vienna (Austria), 15.06.2015

Huber C. G.
A Top-to-Bottom Approach for In-depth Characterization of Therapeutic Monoclonal Antibodies
42nd Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC 2015), Geneva (Switzerland), 21.–25.06.2015

Huber C. G.
From Micro- to Macroanalysis: Microanalytical Methods for Studying Biological Macromolecules
Fritz-Feigl Symposium on Analytical Chemistry 2015, Vienna (Austria), 17.–18.09.2015

Talks

Huber C. G.
Glycosylation Analysis in Biopharmaceutical Development
Live Webinar, 27.04.2015

Gadermaier G.
Structural analysis of Pla l 1, the major Plantago lanceolata allergen, uncovered the Ole e 1-like fold
EAACI Congress 2015, Barcelona (Spain), 06.–10.06.2015

Stock L.
Heat induced transformation of disulphide bonds to lanthionine revealed by capillary electrophoresis
11th ASAC-JunganalytikerInnenforum 2015, Innsbruck (Austria), 12.–13.06.2015

Wohlschlager T.
Intact protein separation by ion-pair reversed phase HPLC: a platform for the systematic characterization of column performance
42nd Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC 2015), Geneva (Switzerland), 21.–25.06.2015

Huber C. G.
Compound Stability: Quantification of Protein Oxidation with Mass Spectrometric Detection – Mission Impossible?
42nd Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC 2015), Geneva (Switzerland), 21.–25.06.2015

Wildner S.
Structure solution of Pla l 1 suggests similar folding of Ole e 1-like family members but distinct immunological properties
ISMA Congress 2015, Lisbon (Portugal), 19.–21.11.2015

Poster Presentations

Samonig M., Scheffler K., Huber C. G.
A Top to Bottom Approach For In-Depth Characterization of Therapeutic Monoclonal Antibodies
48. Jahrestagung der Deutschen Gesellschaft für Massenspektrometrie (DGMS), Wuppertal (Germany), 01.–04.03.2015

Grassi L., Cabrele C.
Toward the chemical synthesis of the CH3 domain IgGI-Fc 345-450 via Ser/Thr based peptide ligation
International Meeting on Peptide & Protein based Materials, Glasgow (United Kingdom), 02.–04.03.2015

Stock L. G., Wildner S., Gadermaier G., Stutz H.
Transformation of disulphide bonds to lanthionine
AT Europe 2015 - Analytical Technologies in the Biopharmaceutical Industry, Berlin (Germany), 17.–20.03.2015

Regl, C., Wohlschlager T., Forstenlehner I. C., Huber C. G.
Forced oxidation of the therapeutic antibody Rituximab: Analytical approaches for the characterization of oxidation variants
AT Europe 2015 - Analytical Technologies in the Biopharmaceutical Industry, Berlin (Germany), 17.-20.03.2015

Wagner I., Samonig M., Holzmann J., Huber C. G.
Rapid characterization of recombinant therapeutic monoclonal antibodies from harvest media by HPLC-MS
AT Europe 2015 - Analytical Technologies in the Biopharmaceutical Industry, Berlin (Germany), 17.-20.03.2015

Regl, C., Weilnböck L., Huber C. G.
Comparison of ERLIC with a new mixed-mode strategy using WCX-RPC for phosphopeptide separation prior to mass spectrometry
Proteomic Forum Berlin 2015, Berlin (Germany), 22.–25.03.2015

Wildner S., Stock L. G., Mari A., Stutz H., Gadermaier G.
The effect of thermal processing on the structural and immunological behavior of Art v 3
EAACI Congress 2015, Barcelona (Spain), 06.–10.06.2015

Menz M., Wohlschlager T., Senn S., Samonig M., Huber C. G.
Optimizing Column Performance for Protein Separation by Ion-Pair reversed Phase HPLC with chromatographic parameters
42nd Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC 2015), Geneva (Switzerland), 21.–25.06.2015

Senn S., Wohlschlager T., Huber C. G.,
A simple combinatorial Approach to identify O-linked Glycosylation Patterns from intact Protein Masses Determined by Mass Spectrometry
Beilstein Glyco-Bioinformatics Symposium 2015, Potsdam (Germany), 22.–26.06.2015

Fegg J., Brandstetter H.
Lysyl Oxidase Catalyzed Stabilization of Proteins
ICA Symposium, Salzburg (Austria), 24.11.2015

Grassi L., Wildner S., Gadermaier G., Cabrele C.
Approaches toward the chemical synthesis of the IgG1 Fc CH3 domain 371-450
5th Austrian Peptide Symposium, Vienna (Austria), 03.12.2015

Participation

Stutz H.
Analytical Technologies in the Biopharmaceutical Industry, Berlin (Germany), 17.–20.03.2015

Stutz H.
11th ASAC-JunganalytikerInnenforum 2015, Innsbruck (Austria), 12.–13.06.2015

Patent Applications

Fegg J., Brandstetter H.
Sensitive Detection of Protein Heterogeneity by use of Enzyme Cascades

Scientific Awards and Honours

Wildner S.
Scholarship EAACI Congress 2015

Wildner S.
ÖGAI travel stipendium
for ISMA Congress 2015

Stock L.
Best Oral Presentation
11. ASAC-Forum of Young Analytical Scientists 2015 in Innsbruck

Huber C. G.
Offer of the Chair of Applied Analytics and Environmental Chemistry of the Humboldt University of Berlin
declined

Regl C.
Master Thesis Award 2015
Austrian Chemical Society (GÖCH)

Organisation of Scientific Events

32nd Winterschool on Proteinases and Inhibitors
Tiers (Italy), 25.02.–01.03.2015