Paper Publications

Peer-reviewed

Regl C., Wohlschlager T., Holzmann J., Huber C. G.
A Generic HPLC Method for Absolute Quantification of Oxidation in Monoclonal Antibodies and Fc-Fusion Proteins Using UV and MS Detection
Anal. Chem. 89(16), 8391–8398 (2017)

Wildner S., Elsässer B., Stemeseder T., Briza P., Soh W. T., Villalba M., Lidholm J., Brandstetter H., Gadermaier G.
Endolysosomal Degradation of Allergenic Ole e 1-Like Proteins: Analysis of Proteolytic Cleavage Sites Revealing T Cell Epitope-Containing Peptides
Int. J. Mol. Sci. 18(8), E1780 (2017)

Stemeseder T., Freier R., Wildner S., Fuchs J. E., Briza P., Lang R., Batanero E., Lidholm J., Liedl K. R., Campo P., Hawranek T., Villalba M., Brandstetter H., Ferreira F., Gadermaier G.
Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1-like protein family
J Allergy Clin Immunol. 140(1), 277–280 (2017)

Grassi L., Regl C., Wildner S., Gadermaier G., Huber C. G., Cabrele C., Schubert M.
Complete NMR Assignment of Succinimide and Its Detection and Quantification in Peptides and Intact Proteins
Anal. Chem. 2017 Nov 7 (Epub ahead of print)

Pablos I., Eichhorn S., Machado Y., Briza P., Neunkirchner A., Jahn-Schmid B., Wildner S., Soh W. T., Ebner C., Park J. W., Pickl W. F., Arora N., Vieths S., Ferreira F., Gadermaier G.
Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to differences in their allergenic activity
Allergy  73(2), 431–441 (2018). Epub ahead of print 2017-09-27

 

Participation in Conferences

Invited Talks

Huber C. G.
Wie „similar“ sind Biosimilars? Biosimilars aus der Sicht eines Chemikers
Fachkonferenz Biosimilars, Mauerbach (Austria), 22.–23.03.2017

Huber C. G.
Characterization of post-translational modifications in therapeutic proteins by HPLC-MS and native MS
Thermo Scientific Biopharma Summit: Shaping the Future Together, Martinsried (Germany), 14.11.2017

Huber C. G.
Analytical Challenges in the Characterization of Therapeutic Proteins by Means of Chromatography and Mass Spectrometry
Anakon 2017, Tübingen (Germany), 03.–06.04.2017

Huber C. G.
Native Mass Spectrometry for the Revelation of Highly Complex Glycosylation in Protein Therapeutics
Proteomic Forum 2017, Potsdam (Germany), 02.–05.04.2017

Huber C. G.
Analytical method development for low- and high-molecular pharmaceuticals: two different worlds?
17th Austrian Chemistry Days, Salzburg (Austria), 25.–28.09.2017

Huber C. G.
Christian Doppler Laboratory for Biosimilar Characterization
Christian Doppler Forum 2017, Krems (Austria), 21.09.2017

Huber C. G.
Christian Doppler Laboratory for Biosimilar Characterization
Information Event "Innovation and Ensuring Scientific Productivity In Salzburg" of the State of Salzburg, Salzburg (Austria), 25.09.2017

Talks

Wohlschlager T.
Native mass spectrometry for the revelation of highly complex glycosylation in biopharmaceuticals
HPLC 2017, Praha, 17.–22.06.2017

Segl M.
Host cell protein identification in biotherapeutics
Doctorate School Data Science, Salzburg, 11.07.2017

Stutz H.
Application and in-capillary characterization of SMIL coatings in capillary electrophoresis separation of proteins
ISSS 2017, Vienna, 19.–22.09.2017

Hollerweger J.
Sensitive detection of protein heterogeneities by using enzyme cascades
34th Winter School on Proteinases and Their Inhibitors, Tiers (Italy), 08.–12.03.2017

Poster Presentations

Wildner S.
Screening of single-stranded DNA aptamers against the monoclonal antibody Rituximab
Aptamers 2017, Oxford, 11.–12.04.2017

Wildner S.
Structural and immunological comparison of heat treated Pru p 3 and Art v 3, the non-specific lipid transfer proteins of peach and mugwort pollen
EAACI Annual Meeting 2017, Helsinki (Finland), 17.–21.06.2017

Regl C.
A Generic HPLC Method for Absolute Quantification of Oxidation in Monoclonal Antibodies and Fc-Fusion Proteins Using UV and MS Detection
Mass Spec 2017, Boston, MA (USA), 19.–22.09.2017

Wohlschlager T.
Native mass spectrometry for the revelation of highly complex glycosylation patterns in biopharmaceuticals
Mass Spec 2017, Boston, MA (USA), 19.–22.09.2017

Segl M.
Host Cell Protein clearance and identification
17th Austrian Chemistry Days, Salzburg (Austria), 25.–28.09.2017

Wildner S.
Identification of IgE-binding epitopes on the surface of the non-specific lipid transfer protein Art v 3
ISMA Congress, Luxembourg, 09.–11.11.2017

Hollerweger J.
Sensitive Detection of Protein Heterogeneity by Use of Enzyme Cascades
BioVaria, München (Germany), 22.–23.05.2017

Participation

Stutz H.
17th Austrian Chemistry Days, Salzburg (Austria), 25.–28.09.2017

Hinterholzer A.
3rd G-NMR School, Berlin (Germany), 18.–22.09.2017

Scientific Awards and Honours

Wohlschlager T.
Poster Prize
Mass Spec 2017

Hollerweger J.
Best talk award
34th Winter School on Proteinases and Their Inhibitors, Tiers (Italy), 08.–12.03.2017

Organisation of Scientific Events

34th Winterschool on Proteinases and Inhibitors
Tiers (Italy), 08.–12.03.2017

National and International Cooperations

C. Herwig
CD-Labor für Mechanistische und physiologische Methoden für leistungsfähigere Bioprozesse, Vienna, Austria

C. Neusüß
Hochschule Aalen, Germany