Paper Publications

Peer-reviewed

Wohlschlager T., Regl C., Huber C. G.
Monitoring of oxidation in biopharmaceuticals with top-to-bottom high performance liquid chromatography–mass spectrometry methodologies: A critical check
LCGC Europe 31(6), 326–331 (2018)

Skala W., Wohlschlager T., Senn S., Huber G. E., Huber C. G.
MoFi: A software tool for annotating glycoprotein mass spectra by integrating hybrid data from the intact protein and glycopeptide level
Anal. Chem. 90(9), 5728–5736 (2018)

Wohlschlager T., Scheffler K., Forstenlehner I. C., Skala W., Senn S., Damoc E., Holzmann J., Huber C. G.
Native mass spectrometry combined with enzymatic dissection unravels glycoform heterogeneity of biopharmaceuticals
Nat. Commun. 9(1), 1713 (2018)

Pablos I., Eichhorn S., Machado Y., Briza P., Neunkirchner A., Jahn-Schmid B., Wildner S., Soh W. T., Ebner C., Park J. W., Pickl W. F., Arora N., Vieths S., Ferreira F., Gadermaier G.
Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to differences in their allergenic activity
Allergy 73(2), 431–441 (2018)

Roschger C., Schubert M., Regl C., Andosch A., Marquez A., Berger T., Huber C. G., Lütz-Meindl U., Cabrele C.
The recombinant inhibitor of DNA binding Id2 forms multimeric structures via the helix-loop-helix domain and the nuclear export signal
Int. J. Mol. Sci. 19(4), E1105 (2018)

Hollerweger J. C., Hoppe I. J., Regl C., Stock L. G., Huber C. G., Lohrig U., Stutz H., Brandstetter H.
Analytical Cascades of Enzymes for sensitive detection of structural variations in protein samples
Anal. Chem. 90(8), 5055–5065 (2018)

Aebersold R., Agar J. N., Amster I. J., Baker M. S., Bertozzi C. R., Boja E. S., Costello C. E., Cravatt B. F., Fenselau C., Garcia B. A., Ge Y., Gunawardena J., Hendrickson R. C., Hergenrother P. J., Huber C. G., Ivanov A. R., Jensen O. N., Jewett M. C., Kelleher N. L., Kiessling L. L., Krogan N. J., Larsen M. R., Loo J. A., Ogorzalek Loo R. R., Lundberg E., MacCoss M. J., Mallick P., Mootha V. K., Mrksich M., Muir T. W., Patrie S. M., Pesavento J. J., Pitteri S. J., Rodriguez H., Saghatelian A., Sandoval W., Schlüter H., Sechi S., Slavoff S. A., Smith L. M., Snyder M. P., Thomas P. M., Uhlén M., Van Eyk J. E., Vidal M., Walt D. R., White F. M., Williams E. R., Wohlschlager T., Wysocki V. H., Yates N. A., Young N. L., Zhang B.
How many human proteoforms are there?
Nat. Chem. Biol. 14(3), 206–214 (2018)

Zauner F. B., Dall E., Regl C., Grassi L., Huber C. G., Cabrele C., Brandstetter H.
Crystal structure of plant legumain reveals a unique two-chain state with pH-dependent activity regulation
Plant Cell 30(3), 686–699 (2018)

Participation in Conferences

Invited Talks

Gadermaier G.
Detection of proteins and biopharmaceuticals using aptamers
Analytica, München (Germany), 10.04.2018

Huber C. G.
HPLC-MS and Native MS Approaches to the Characterization of Posttranslational Modifications in Biopharmaceuticals
Analytica, München (Germany), 12.04.2018

Huber C. G.
Microscale and capillary scale HPLC-MS methods for biopharmaceutical analysis
International Symposium on Capillary Chromatography, Riva del Garda(Italy), 13.–18.05.2018

Talks

Regl C.
A Generic HPLC Method for Absolute Quantification of Oxidation in Monoclonal Antibodies and Fc-Fusion Proteins Using UV and MS Detection
35th Agilent Forum Analytik, Vienna (Austria), 13.02.2018

Schubert M.
Detection of succinimide as degradation product in proteins
Central European NMR Meeting, Valtice (Czech Republic), 23.–25.05.2018 

Poster Presentations

 

Participation

Hinterholzer A.
Central European NMR Meeting, Valtice (Czech Republic), 23.–25.05.2018 

Scientific Awards and Honours

Wohlschlager T.
Publication of the Month June
Department of Biosciences, University of Salzburg, for her paper in Nature Communications (see above)

Organisation of Scientific Events

35th Winterschool on Proteinases and Inhibitors
Tiers (Italy), 28.02.–04.03.2018

National and International Cooperations

A. Bathke, W. Trutschnig
Statistics and Probability Research Group, Department of Mathematics, University of Salzburg, Austria

J. Bones
National Institute for Bioprocessing Research & Training (NIBRT), Dublin, Ireland

O. Kohlbacher
Applied Bioinformatics Group, University of Tübingen, Germany